Plant Transcription Factor Database
Previous version: v3.0
Nicotiana tabacum
NF-YB Family
Species TF ID Description
XP_016434682.1NF-YB family protein
XP_016435625.1NF-YB family protein
XP_016436262.1NF-YB family protein
XP_016438472.1NF-YB family protein
XP_016438654.1NF-YB family protein
XP_016439618.1NF-YB family protein
XP_016439627.1NF-YB family protein
XP_016440201.1NF-YB family protein
XP_016441192.1NF-YB family protein
XP_016447154.1NF-YB family protein
XP_016449854.1NF-YB family protein
XP_016449855.1NF-YB family protein
XP_016449856.1NF-YB family protein
XP_016450626.1NF-YB family protein
XP_016452159.1NF-YB family protein
XP_016456590.1NF-YB family protein
XP_016456591.1NF-YB family protein
XP_016458099.1NF-YB family protein
XP_016458530.1NF-YB family protein
XP_016459816.1NF-YB family protein
XP_016459921.1NF-YB family protein
XP_016460750.1NF-YB family protein
XP_016462866.1NF-YB family protein
XP_016464437.1NF-YB family protein
XP_016464438.1NF-YB family protein
XP_016471364.1NF-YB family protein
XP_016476361.1NF-YB family protein
XP_016480254.1NF-YB family protein
XP_016487102.1NF-YB family protein
XP_016488041.1NF-YB family protein
XP_016488048.1NF-YB family protein
XP_016488182.1NF-YB family protein
XP_016488440.1NF-YB family protein
XP_016489475.1NF-YB family protein
XP_016489556.1NF-YB family protein
XP_016490537.1NF-YB family protein
XP_016492392.1NF-YB family protein
XP_016498596.1NF-YB family protein
XP_016510771.1NF-YB family protein
XP_016510778.1NF-YB family protein
XP_016510785.1NF-YB family protein
NF-YB Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

As with NF-YA, NF-YB and NF-YC families have well-described subunit interaction and DNA-binding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NF-YB and NF-YC have structural and amino acid homology to histone fold motifs. Specifically, NF-YB is related to the histone fold motifs of H2B histones, while NF-YC subunits are related to H2A histones (Mantovani, 1999).

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982